Abstract: To elucidate the distribution characteristics and potential ecological risks of trace organic contaminants (TrOCs) in industrial park wastewater treatment plants (WWTPs),a WWTP in Guang'an Economic Development Zone was selected as the research object.Non-targeted screening was conducted using solid-phase extraction in conjunction with ultra-high performance liquid chromatography - quadrupole time of - flight mass spectrometry (SPE-UHPLC-QTOF-MS).Following identification,the top ten high-concentration and high-toxicity pollutants were selected for quantitative detection.The results showed that the concentrations of the target TrOCs ranged from 0.34 to 80280 μg/L,among which nitrilotriacetic acid and cyclododecanone were significantly higher than the others.In terms of removal behaviors,the concentrations of nitrilotriacetic acid,N-acetyl-1-naphthylamine,and 3-methyldiphenylamine increased during the biological treatment stage,whereas advanced treatment with activated carbon achieved remarkable removal for most pollutants,with an overall removal rate of 100%.Correlation analysis revealed that ammonia nitrogen and total nitrogen were significantly positively correlated with TrOCs concentrations,indicating that enhanced nitrogen removal may facilitate the synergistic control of TrOCs.The ecological risk evaluation revealed that dodecanamide,nitrilotriacetic acid,isoprothiolane,amitriptyline,3-methylbenzenediamine,cyclododecanone,and N-acetyl-1-aminonaphthalene pose potential ecological risks,which underscores the need for enhanced source control.This study provides a scientific basis for the source management of high-risk contaminants and the optimization of wastewater treatment technologies.